منابع مشابه
Emerging Drug Therapies for Heart Failure
Heart failure is associated with high morbidity and mortality and is proving to be an economic burden in developing countries. A number of therapeutic agents are presently employed in heart failure; but they are not sufficient to control symptoms of heart failure. Moreover, the prevalence of chronic heart failure is progressively increasing and thus there is a continuing need to develop effecti...
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In the United States alone, about 250,000 people develop significant mitral regurgitation (MR) each year, with almost 50,000 undergoing surgery. Surgical repair of a diseased mitral valve has become the treatment of choice for patients with significant MR. Since there is no single therapeutic approach for every etiology of MR, surgical mitral valve repair includes a variety of techniques that a...
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Although several effective therapies are available for the treatment of osteoporosis in postmenopausal women and older men, there remains a need for the development of even more effective and acceptable drugs. Several new drugs that are in late-stage clinical development will be discussed. Abaloparatide (recombinant parathyroid hormone related peptide [PTHrP] analogue) has anabolic activity lik...
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The results of the European Cooperative Acute Stroke Study III (ECASS III) provide an important advance for the field of acute stroke therapy. The study was well-designed and conducted. The trial provides unequivocal and straightforward evidence that treatment with intravenous (IV) tissue plasminogen activator (tPA) initiated 3 to 4.5 hours after the onset of ischemic stroke improves 90-day out...
متن کاملEmerging Therapies
Indirect comparisons of CAPRIE, ESPS-2, and MATCH trials led many stroke experts to favor the combination of aspirin and extended-release dipyridamole (ASA/ERD) over clopidogrel as the preferred antiplatelet therapy for secondary stroke prevention.1–3 The Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) study, a 2 2 factorial, double-blind, event-driven, active and placebo-c...
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ژورنال
عنوان ژورنال: Journal of Gastroenterology
سال: 2020
ISSN: 0944-1174,1435-5922
DOI: 10.1007/s00535-020-01664-0